Registered Nurses pay range in Spartanburg
New workers and the lowest-paid 10% earn about $70,180 a year or less, while the top 10% make $101,420 or more. The middle half of registered nurses in Spartanburg earn between $70,250 and $85,470.
- $70K10th
- $70K25th
- $82KMedian
- $85K75th
- $101K90th
median average · bar = middle 50% of workers · how to read it
| Pay level | Per year | Per month | Per hour* |
|---|---|---|---|
| Average | $84,020 | $7,002 | $40.39 |
| Median | $82,360 | $6,863 | $39.60 |
| Entry level (25th percentile) | $70,250 | $5,854 | $33.77 |
| Experienced (75th percentile) | $85,470 | $7,122 | $41.09 |
*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.
Registered Nurses pay in Spartanburg vs. South Carolina and the U.S.
Registered nurses in Spartanburg earn 4% less than the South Carolina average ($87,670) and 17% less than the U.S. average ($101,420). At the median the gap is -16% against the U.S. median of $97,550.
| Area | Average | Median | 10th pct. | 90th pct. | Jobs |
|---|---|---|---|---|---|
| Spartanburg | $84,020 | $82,360 | $70,180 | $101,420 | 4,440 |
| South Carolina | $87,670 | $82,360 | $66,860 | $106,520 | 49,750 |
| United States | $101,420 | $97,550 | $68,940 | $137,470 | 3,379,720 |
State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.
Registered Nurses salary after taxes in Spartanburg
On the average salary of $84,020, a single filer in Spartanburg takes home about $64,683 a year, or $5,390 a month and $2,488 every two weeks. Taxes take 23% of gross pay.
Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules).
Is Spartanburg a good place for registered nurses? Pay vs. cost of living
Prices in the Spartanburg area are 9% below the U.S. average (BEA price parity 91.1), so the average $84,020 buys what about $92,278 would buy in a typical U.S. metro. This job pays 1.7 times the median wage of all jobs in Spartanburg ($47,650). A typical home costs $279,792, or 3.3 years of this average salary before tax.
Registered Nurses salary in other South Carolina cities
Spartanburg ranks 6th of 8 South Carolina metro areas for this job; Florence pays the most ($100,700).
- Florence$100,700
- Charleston$91,710
- Columbia$88,030
- Greenville$85,030
- Sumter$84,470
- Spartanburg$84,020
- Myrtle Beach$82,860
- Hilton Head Island$82,270
Highest-paying cities for registered nurses
San Jose, CA pays this job the most of the metro areas we cover ($194,950).
- San Jose, CA$194,950
- Vallejo, CA$182,820
- San Francisco, CA$176,900
- Santa Rosa, CA$170,000
- Sacramento, CA$164,200
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Registered Nurses salary in Spartanburg: questions
How much do registered nurses make an hour in Spartanburg?
$40.39 an hour on average, and $39.60 at the median (BLS, May 2025).
What is the entry-level registered nurses salary in Spartanburg?
The lowest-paid 10% earn about $70,180 a year and the 25th percentile is $70,250, a fair guide to starting pay.
What is the registered nurses take-home pay in Spartanburg?
About $64,683 a year ($5,390 a month) for a single filer on the average salary of $84,020.
Do registered nurses earn more in Spartanburg than elsewhere?
The average here is 17% less than the U.S. average for this job ($101,420).
Sources and how to read this page
- Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1141; area Spartanburg, SC (43900). Relative standard error of the mean wage: 1.0%.
- U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
- Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
- Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
- Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules).
- Job concentration: location quotient 1.24, this job is about as common as in the U.S. overall.
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