Registered Nurses pay range in Florence
New workers and the lowest-paid 10% earn about $65,710 a year or less, while the top 10% make $174,900 or more. The middle half of registered nurses in Florence earn between $66,860 and $125,840.
- $66K10th
- $67K25th
- $81KMedian
- $126K75th
- $175K90th
median average · bar = middle 50% of workers
| Pay level | Per year | Per month | Per hour* |
|---|---|---|---|
| Average | $100,700 | $8,392 | $48.41 |
| Median | $81,170 | $6,764 | $39.02 |
| Entry level (25th percentile) | $66,860 | $5,572 | $32.14 |
| Experienced (75th percentile) | $125,840 | $10,487 | $60.50 |
*Hourly figures assume 2,080 paid hours a year.
Registered Nurses salary after taxes in Florence
On the average salary of $100,700, a single filer in Florence takes home about $75,392 a year, or $6,283 a month and $2,900 every two weeks. Taxes take 25% of gross pay.
Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules).
Is Florence a good place for registered nurses? Pay vs. cost of living
Prices in the Florence area are 13% below the U.S. average (BEA price parity 86.8), so the average $100,700 buys what about $116,049 would buy in a typical U.S. metro. This job pays 1.9 times the median wage of all jobs in Florence ($43,520). A typical home costs $193,792, or 1.9 years of this average salary before tax.
Registered Nurses salary in other South Carolina cities
Florence ranks 1st of 8 South Carolina metro areas for this job, the best-paid in the state.
- Florence$100,700
- Charleston$91,710
- Columbia$88,030
- Greenville$85,030
- Sumter$84,470
- Spartanburg$84,020
- Myrtle Beach$82,860
- Hilton Head Island$82,270
Highest-paying cities for registered nurses
San Jose, CA pays this job the most of the metro areas we cover ($194,950).
- San Jose, CA$194,950
- Vallejo, CA$182,820
- San Francisco, CA$176,900
- Santa Rosa, CA$170,000
- Sacramento, CA$164,200
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Registered Nurses salary in Florence: questions
How much do registered nurses make an hour in Florence?
$48.41 an hour on average, and $39.02 at the median (BLS, May 2025).
What is the entry-level registered nurses salary in Florence?
The lowest-paid 10% earn about $65,710 a year and the 25th percentile is $66,860, a fair guide to starting pay.
What is the registered nurses take-home pay in Florence?
About $75,392 a year ($6,283 a month) for a single filer on the average salary of $100,700.
Do registered nurses earn more in Florence than elsewhere?
The average here is about the same as the U.S. metro average for this job ($102,761).
Sources and how to read this page
- Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1141; area Florence, SC (22500). Relative standard error of the mean wage: 0.8%.
- Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
- Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
- Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules).
- Job concentration: location quotient 1.61, this job is 1.6 times as concentrated as in the U.S. overall.
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