Physician Assistants Salary in South Dakota

Physician assistants in South Dakota earn the most in Sioux Falls (average $132,350 a year) and the least in Rapid City ($129,590), across the 2 South Dakota metro areas we cover. Statewide, BLS puts the physician assistants average at $131,910 and the median at $133,200 for 680 workers. The U.S. average for this job is $141,280.

Physician Assistants average salary by city in South Dakota

Sioux Falls$132,350
Rapid City$129,590

Pay, take-home pay and cost of living

City	Average	Median	25th pct.	Take-home*	Cost of living
Sioux Falls	$132,350	$135,790	$110,150	$101,727	91
Rapid City	$129,590	$130,740	$113,340	$99,841	89

*Average salary after federal and state taxes for a single filer; South Dakota has no state income tax. Cost of living: BEA price parity, U.S. = 100.

Physician Assistants salary in other states

Physician Assistants salary by city and state

More about pay in South Dakota

Sources and how to read this page

Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1071.
U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.

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