Physician Assistants pay range in Buffalo
New workers and the lowest-paid 10% earn about $98,820 a year or less, while the top 10% make $160,880 or more. The middle half of physician assistants in Buffalo earn between $105,240 and $144,810.
- $99K10th
- $105K25th
- $126KMedian
- $145K75th
- $161K90th
median average · bar = middle 50% of workers · how to read it
| Pay level | Per year | Per month | Per hour* |
|---|---|---|---|
| Average | $127,510 | $10,626 | $61.30 |
| Median | $126,360 | $10,530 | $60.75 |
| Entry level (25th percentile) | $105,240 | $8,770 | $50.60 |
| Experienced (75th percentile) | $144,810 | $12,068 | $69.62 |
*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.
Physician Assistants pay in Buffalo vs. New York and the U.S.
Physician assistants in Buffalo earn 18% less than the New York average ($155,150) and 10% less than the U.S. average ($141,280). At the median the gap is -7% against the U.S. median of $135,880.
| Area | Average | Median | 10th pct. | 90th pct. | Jobs |
|---|---|---|---|---|---|
| Buffalo | $127,510 | $126,360 | $98,820 | $160,880 | 1,040 |
| New York | $155,150 | $160,880 | $106,440 | $201,410 | 19,140 |
| United States | $141,280 | $135,880 | $99,380 | $190,280 | 162,150 |
State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.
Physician Assistants salary after taxes in Buffalo
On the average salary of $127,510, a single filer in Buffalo takes home about $91,817 a year, or $7,651 a month and $3,531 every two weeks. Taxes take 28% of gross pay.
Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2025 rules). New York City (up to 3.876%) and Yonkers income taxes are not included.
Is Buffalo a good place for physician assistants? Pay vs. cost of living
Prices in the Buffalo area are 4% below the U.S. average (BEA price parity 95.8), so the average $127,510 buys what about $133,039 would buy in a typical U.S. metro. This job pays 2.5 times the median wage of all jobs in Buffalo ($50,790). A typical home costs $288,316, or 2.3 years of this average salary before tax.
Physician Assistants salary in other New York cities
Buffalo ranks 13th of 13 New York metro areas for this job; New York pays the most ($163,570).
- New York$163,570
- Binghamton$149,840
- Kiryas Joel$149,140
- Kingston$146,020
- Ithaca$143,860
- Albany$140,600
- Utica$139,930
- Syracuse$135,060
- Elmira$133,490
- Buffalo$127,510
Highest-paying cities for physician assistants
San Jose, CA pays this job the most of the metro areas we cover ($207,660).
- San Jose, CA$207,660
- Salinas, CA$202,320
- San Francisco, CA$182,610
- Vallejo, CA$182,520
- Bakersfield, CA$177,840
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Physician Assistants salary in Buffalo: questions
How much do physician assistants make an hour in Buffalo?
$61.30 an hour on average, and $60.75 at the median (BLS, May 2025).
What is the entry-level physician assistants salary in Buffalo?
The lowest-paid 10% earn about $98,820 a year and the 25th percentile is $105,240, a fair guide to starting pay.
What is the physician assistants take-home pay in Buffalo?
About $91,817 a year ($7,651 a month) for a single filer on the average salary of $127,510. New York City (up to 3.876%) and Yonkers income taxes are not included.
Do physician assistants earn more in Buffalo than elsewhere?
The average here is 10% less than the U.S. average for this job ($141,280).
Sources and how to read this page
- Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1071; area Buffalo-Cheektowaga, NY (15380). Relative standard error of the mean wage: 1.9%.
- U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
- Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
- Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
- Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2025 rules). New York City (up to 3.876%) and Yonkers income taxes are not included.
- Job concentration: location quotient 1.87, this job is 1.9 times as concentrated as in the U.S. overall.
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