Physician Assistants pay range in Jefferson City
New workers and the lowest-paid 10% earn about $105,440 a year or less, while the top 10% make $161,140 or more. The middle half of physician assistants in Jefferson City earn between $120,740 and $161,140.
- $105K10th
- $121K25th
- $135KMedian
- $161K75th
- $161K90th
median average · bar = middle 50% of workers · how to read it
| Pay level | Per year | Per month | Per hour* |
|---|---|---|---|
| Average | $135,650 | $11,304 | $65.22 |
| Median | $135,340 | $11,278 | $65.07 |
| Entry level (25th percentile) | $120,740 | $10,062 | $58.05 |
| Experienced (75th percentile) | $161,140 | $13,428 | $77.47 |
*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.
Physician Assistants pay in Jefferson City vs. Missouri and the U.S.
Physician assistants in Jefferson City earn about the same as the Missouri average ($137,710) and 4% less than the U.S. average ($141,280). At the median the gap is -0% against the U.S. median of $135,880.
| Area | Average | Median | 10th pct. | 90th pct. | Jobs |
|---|---|---|---|---|---|
| Jefferson City | $135,650 | $135,340 | $105,440 | $161,140 | 40 |
| Missouri | $137,710 | $135,130 | $82,690 | $169,650 | 2,300 |
| United States | $141,280 | $135,880 | $99,380 | $190,280 | 162,150 |
State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.
Physician Assistants salary after taxes in Jefferson City
On the average salary of $135,650, a single filer in Jefferson City takes home about $98,545 a year, or $8,212 a month and $3,790 every two weeks. Taxes take 27% of gross pay.
Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules). The 1% earnings tax applies to people who live or work in Kansas City or St. Louis itself, not in the suburbs.
Is Jefferson City a good place for physician assistants? Pay vs. cost of living
Prices in the Jefferson City area are 12% below the U.S. average (BEA price parity 88.0), so the average $135,650 buys what about $154,192 would buy in a typical U.S. metro. This job pays 2.8 times the median wage of all jobs in Jefferson City ($48,030). A typical home costs $275,951, or 2.0 years of this average salary before tax.
Physician Assistants salary in other Missouri cities
Jefferson City ranks 6th of 8 Missouri metro areas for this job; Joplin pays the most ($142,860).
- Joplin$142,860
- Cape Girardeau$140,770
- St. Joseph$137,640
- St. Louis$137,450
- Springfield$136,330
- Jefferson City$135,650
- Kansas City$134,340
- Columbia$132,510
Highest-paying cities for physician assistants
San Jose, CA pays this job the most of the metro areas we cover ($207,660).
- San Jose, CA$207,660
- Salinas, CA$202,320
- San Francisco, CA$182,610
- Vallejo, CA$182,520
- Bakersfield, CA$177,840
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Physician Assistants salary in Jefferson City: questions
How much do physician assistants make an hour in Jefferson City?
$65.22 an hour on average, and $65.07 at the median (BLS, May 2025).
What is the entry-level physician assistants salary in Jefferson City?
The lowest-paid 10% earn about $105,440 a year and the 25th percentile is $120,740, a fair guide to starting pay.
What is the physician assistants take-home pay in Jefferson City?
About $98,545 a year ($8,212 a month) for a single filer on the average salary of $135,650. The 1% earnings tax applies to people who live or work in Kansas City or St. Louis itself, not in the suburbs.
Do physician assistants earn more in Jefferson City than elsewhere?
The average here is 4% less than the U.S. average for this job ($141,280).
Sources and how to read this page
- Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1071; area Jefferson City, MO (27620). Relative standard error of the mean wage: 2.0%.
- U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
- Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
- Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
- Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules). The 1% earnings tax applies to people who live or work in Kansas City or St. Louis itself, not in the suburbs.
- Job concentration: location quotient 0.45, this job is less common than in the U.S. overall (location quotient 0.45).
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