Nurse Practitioners pay range in Buffalo
New workers and the lowest-paid 10% earn about $104,470 a year or less, while the top 10% make $166,300 or more. The middle half of nurse practitioners in Buffalo earn between $111,890 and $150,400.
- $104K10th
- $112K25th
- $132KMedian
- $150K75th
- $166K90th
median average · bar = middle 50% of workers
| Pay level | Per year | Per month | Per hour* |
|---|---|---|---|
| Average | $135,110 | $11,259 | $64.96 |
| Median | $132,220 | $11,018 | $63.57 |
| Entry level (25th percentile) | $111,890 | $9,324 | $53.79 |
| Experienced (75th percentile) | $150,400 | $12,533 | $72.31 |
*Hourly figures assume 2,080 paid hours a year.
Nurse Practitioners salary after taxes in Buffalo
On the average salary of $135,110, a single filer in Buffalo takes home about $96,555 a year, or $8,046 a month and $3,714 every two weeks. Taxes take 29% of gross pay.
Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2025 rules). New York City (up to 3.876%) and Yonkers income taxes are not included.
Is Buffalo a good place for nurse practitioners? Pay vs. cost of living
Prices in the Buffalo area are 4% below the U.S. average (BEA price parity 95.8), so the average $135,110 buys what about $140,969 would buy in a typical U.S. metro. This job pays 2.6 times the median wage of all jobs in Buffalo ($50,790). A typical home costs $288,316, or 2.1 years of this average salary before tax.
Nurse Practitioners salary in other New York cities
Buffalo ranks 10th of 13 New York metro areas for this job; New York pays the most ($162,620).
- New York$162,620
- Kingston$154,030
- Kiryas Joel$146,490
- Binghamton$145,400
- Ithaca$143,840
- Glens Falls$142,170
- Elmira$138,270
- Albany$136,720
- Watertown$135,170
- Buffalo$135,110
Highest-paying cities for nurse practitioners
San Jose, CA pays this job the most of the metro areas we cover ($225,610).
- San Jose, CA$225,610
- San Francisco, CA$215,430
- Vallejo, CA$196,780
- Napa, CA$188,720
- Modesto, CA$187,690
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Nurse Practitioners salary in Buffalo: questions
How much do nurse practitioners make an hour in Buffalo?
$64.96 an hour on average, and $63.57 at the median (BLS, May 2025).
What is the entry-level nurse practitioners salary in Buffalo?
The lowest-paid 10% earn about $104,470 a year and the 25th percentile is $111,890, a fair guide to starting pay.
What is the nurse practitioners take-home pay in Buffalo?
About $96,555 a year ($8,046 a month) for a single filer on the average salary of $135,110. New York City (up to 3.876%) and Yonkers income taxes are not included.
Do nurse practitioners earn more in Buffalo than elsewhere?
The average here is about the same as the U.S. metro average for this job ($138,268).
Sources and how to read this page
- Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1171; area Buffalo-Cheektowaga, NY (15380). Relative standard error of the mean wage: 1.3%.
- Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
- Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
- Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2025 rules). New York City (up to 3.876%) and Yonkers income taxes are not included.
- Job concentration: location quotient 1.07, this job is about as common as in the U.S. overall.
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