Registered Nurses Salary in South Dakota

Registered nurses in South Dakota earn the most in Rapid City (average $84,070 a year) and the least in Sioux Falls ($74,700), across the 2 South Dakota metro areas we cover. Statewide, BLS puts the registered nurses average at $77,140 and the median at $78,060 for 14,710 workers. The U.S. average for this job is $101,420.

Registered Nurses average salary by city in South Dakota

Rapid City$84,070
Sioux Falls$74,700

Pay, take-home pay and cost of living

City	Average	Median	25th pct.	Take-home*	Cost of living
Rapid City	$84,070	$79,380	$69,090	$67,973	89
Sioux Falls	$74,700	$75,350	$65,070	$61,381	91

*Average salary after federal and state taxes for a single filer; South Dakota has no state income tax. Cost of living: BEA price parity, U.S. = 100.

Registered Nurses salary in other states

Registered Nurses salary by city and state

More about pay in South Dakota

Sources and how to read this page

Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1141.
U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.

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