SOC 29-1141 · Columbia, MO metro

Registered Nurses Salary in Columbia, MO

The average salary for registered nurses in Columbia, Missouri is $85,120 a year ($40.92 an hour), according to BLS estimates for May 2025. The median is $84,330: half of the 3,680 people in this job in the Columbia, MO metro area earn more than that, half earn less. That average is 17% less than the U.S. metro average for this job ($102,761).

$85,120average per year

$40.92 / hourMedian $84,330Take-home ≈ $65,649

  • $63K10th
  • $69K25th
  • $84KMedian
  • $93K75th
  • $106K90th

median average · bar = middle 50% of workers

3,680people in this job
-17%vs U.S. metro average
#5 of 8Missouri metros
89cost of living (U.S. = 100)
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Registered Nurses pay range in Columbia

New workers and the lowest-paid 10% earn about $63,080 a year or less, while the top 10% make $105,790 or more. The middle half of registered nurses in Columbia earn between $68,930 and $93,390.

  • $63K10th
  • $69K25th
  • $84KMedian
  • $93K75th
  • $106K90th

median average · bar = middle 50% of workers

Pay levelPer yearPer monthPer hour*
Average$85,120$7,093$40.92
Median$84,330$7,028$40.54
Entry level (25th percentile)$68,930$5,744$33.14
Experienced (75th percentile)$93,390$7,782$44.90

*Hourly figures assume 2,080 paid hours a year.

Registered Nurses salary after taxes in Columbia

On the average salary of $85,120, a single filer in Columbia takes home about $65,649 a year, or $5,471 a month and $2,525 every two weeks. Taxes take 23% of gross pay.

Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules). The 1% earnings tax applies to people who live or work in Kansas City or St. Louis itself, not in the suburbs.

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Is Columbia a good place for registered nurses? Pay vs. cost of living

Prices in the Columbia area are 11% below the U.S. average (BEA price parity 89.4), so the average $85,120 buys what about $95,172 would buy in a typical U.S. metro. This job pays 1.8 times the median wage of all jobs in Columbia ($47,260). A typical home costs $323,951, or 3.8 years of this average salary before tax.

See what $85,120 is worth in another city

Registered Nurses salary in other Missouri cities

Columbia ranks 5th of 8 Missouri metro areas for this job; Jefferson City pays the most ($92,700).

All Registered Nurses salaries in Missouri

Highest-paying cities for registered nurses

San Jose, CA pays this job the most of the metro areas we cover ($194,950).

Registered Nurses salary by city

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Reviewed before it counts. Registered Nurses in Columbia, MO.

Registered Nurses salary in Columbia: questions

How much do registered nurses make an hour in Columbia?

$40.92 an hour on average, and $40.54 at the median (BLS, May 2025).

What is the entry-level registered nurses salary in Columbia?

The lowest-paid 10% earn about $63,080 a year and the 25th percentile is $68,930, a fair guide to starting pay.

What is the registered nurses take-home pay in Columbia?

About $65,649 a year ($5,471 a month) for a single filer on the average salary of $85,120. The 1% earnings tax applies to people who live or work in Kansas City or St. Louis itself, not in the suburbs.

Do registered nurses earn more in Columbia than elsewhere?

The average here is 17% less than the U.S. metro average for this job ($102,761).

Sources and how to read this page

  • Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1141; area Columbia, MO (17860). Relative standard error of the mean wage: 0.5%.
  • Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
  • Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
  • Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules). The 1% earnings tax applies to people who live or work in Kansas City or St. Louis itself, not in the suburbs.
  • Job concentration: location quotient 1.57, this job is 1.6 times as concentrated as in the U.S. overall.

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