Registered Nurses pay range in Des Moines
New workers and the lowest-paid 10% earn about $64,680 a year or less, while the top 10% make $100,500 or more. The middle half of registered nurses in Des Moines earn between $70,070 and $86,690.
- $65K10th
- $70K25th
- $79KMedian
- $87K75th
- $100K90th
median average · bar = middle 50% of workers
| Pay level | Per year | Per month | Per hour* |
|---|---|---|---|
| Average | $81,710 | $6,809 | $39.28 |
| Median | $78,630 | $6,552 | $37.80 |
| Entry level (25th percentile) | $70,070 | $5,839 | $33.69 |
| Experienced (75th percentile) | $86,690 | $7,224 | $41.68 |
*Hourly figures assume 2,080 paid hours a year.
Registered Nurses salary after taxes in Des Moines
On the average salary of $81,710, a single filer in Des Moines takes home about $63,820 a year, or $5,318 a month and $2,455 every two weeks. Taxes take 22% of gross pay.
Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules). Iowa school district surtaxes (a percentage of state tax in some districts) are not included.
Is Des Moines a good place for registered nurses? Pay vs. cost of living
Prices in the Des Moines area are 8% below the U.S. average (BEA price parity 91.7), so the average $81,710 buys what about $89,105 would buy in a typical U.S. metro. This job pays 1.5 times the median wage of all jobs in Des Moines ($51,820). A typical home costs $296,070, or 3.6 years of this average salary before tax.
Registered Nurses salary in other Iowa cities
Des Moines ranks 2nd of 8 Iowa metro areas for this job; Iowa City pays the most ($85,670).
- Iowa City$85,670
- Des Moines$81,710
- Cedar Rapids$80,160
- Dubuque$79,120
- Davenport$78,800
- Ames$76,910
- Waterloo$76,500
- Sioux City$75,840
Highest-paying cities for registered nurses
San Jose, CA pays this job the most of the metro areas we cover ($194,950).
- San Jose, CA$194,950
- Vallejo, CA$182,820
- San Francisco, CA$176,900
- Santa Rosa, CA$170,000
- Sacramento, CA$164,200
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Registered Nurses salary in Des Moines: questions
How much do registered nurses make an hour in Des Moines?
$39.29 an hour on average, and $37.80 at the median (BLS, May 2025).
What is the entry-level registered nurses salary in Des Moines?
The lowest-paid 10% earn about $64,680 a year and the 25th percentile is $70,070, a fair guide to starting pay.
What is the registered nurses take-home pay in Des Moines?
About $63,820 a year ($5,318 a month) for a single filer on the average salary of $81,710. Iowa school district surtaxes (a percentage of state tax in some districts) are not included.
Do registered nurses earn more in Des Moines than elsewhere?
The average here is 20% less than the U.S. metro average for this job ($102,761).
Sources and how to read this page
- Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1141; area Des Moines-West Des Moines, IA (19780). Relative standard error of the mean wage: 0.9%.
- Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
- Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
- Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules). Iowa school district surtaxes (a percentage of state tax in some districts) are not included.
- Job concentration: location quotient 0.93, this job is about as common as in the U.S. overall.
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