SOC 29-1071 · San Antonio-New Braunfels, TX metro

Physician Assistants Salary in San Antonio, TX

The average salary for physician assistants in San Antonio, Texas is $144,100 a year ($69.28 an hour), according to BLS estimates for May 2025. The median is $140,160: half of the 650 people in this job in the San Antonio-New Braunfels, TX metro area earn more than that, half earn less. That average is about the same as the U.S. average for this job ($141,280).

$144,100average per year

$69.28 / hourMedian $140,160Take-home ≈ $109,758

  • $114K10th
  • $128K25th
  • $140KMedian
  • $154K75th
  • $202K90th

median average · bar = middle 50% of workers · how to read it

650people in this job
+2%vs U.S. average
#2 of 21Texas metros
95cost of living (U.S. = 100)
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Physician Assistants pay range in San Antonio

New workers and the lowest-paid 10% earn about $113,840 a year or less, while the top 10% make $201,640 or more. The middle half of physician assistants in San Antonio earn between $128,070 and $154,110.

  • $114K10th
  • $128K25th
  • $140KMedian
  • $154K75th
  • $202K90th

median average · bar = middle 50% of workers · how to read it

Pay levelPer yearPer monthPer hour*
Average$144,100$12,008$69.28
Median$140,160$11,680$67.38
Entry level (25th percentile)$128,070$10,672$61.57
Experienced (75th percentile)$154,110$12,842$74.09

*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.

Physician Assistants pay in San Antonio vs. Texas and the U.S.

Physician assistants in San Antonio earn 6% more than the Texas average ($135,850) and about the same as the U.S. average ($141,280). At the median the gap is +3% against the U.S. median of $135,880.

AreaAverageMedian10th pct.90th pct.Jobs
San Antonio$144,100$140,160$113,840$201,640650
Texas$135,850$134,550$102,650$169,00010,110
United States$141,280$135,880$99,380$190,280162,150

State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.

Physician Assistants salary after taxes in San Antonio

On the average salary of $144,100, a single filer in San Antonio takes home about $109,758 a year, or $9,147 a month and $4,221 every two weeks. Taxes take 24% of gross pay.

Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and no state income tax.

Texas paycheck calculator: try your own salary

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Is San Antonio a good place for physician assistants? Pay vs. cost of living

Prices in the San Antonio area are 5% below the U.S. average (BEA price parity 94.7), so the average $144,100 buys what about $152,139 would buy in a typical U.S. metro. This job pays 3.0 times the median wage of all jobs in San Antonio ($47,010). A typical home costs $280,297, or 1.9 years of this average salary before tax.

See what $144,100 is worth in another city

Physician Assistants salary in other Texas cities

San Antonio ranks 2nd of 21 Texas metro areas for this job; Killeen pays the most ($144,350).

All Physician Assistants salaries in Texas

Highest-paying cities for physician assistants

San Jose, CA pays this job the most of the metro areas we cover ($207,660).

Physician Assistants salary by city

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Reviewed before it counts. Physician Assistants in San Antonio, TX.

Physician Assistants salary in San Antonio: questions

How much do physician assistants make an hour in San Antonio?

$69.28 an hour on average, and $67.38 at the median (BLS, May 2025).

What is the entry-level physician assistants salary in San Antonio?

The lowest-paid 10% earn about $113,840 a year and the 25th percentile is $128,070, a fair guide to starting pay.

What is the physician assistants take-home pay in San Antonio?

About $109,758 a year ($9,147 a month) for a single filer on the average salary of $144,100. Texas has no state income tax.

Do physician assistants earn more in San Antonio than elsewhere?

The average here is about the same as the U.S. average for this job ($141,280).

Sources and how to read this page

  • Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1071; area San Antonio-New Braunfels, TX (41700). Relative standard error of the mean wage: 2.5%.
  • U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
  • Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
  • Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
  • Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and no state income tax.
  • Job concentration: location quotient 0.55, this job is less common than in the U.S. overall (location quotient 0.55).

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