Nurse Practitioners pay range in Greenville
New workers and the lowest-paid 10% earn about $81,910 a year or less, while the top 10% make $145,570 or more. The middle half of nurse practitioners in Greenville earn between $110,030 and $129,900.
- $82K10th
- $110K25th
- $119KMedian
- $130K75th
- $146K90th
median average · bar = middle 50% of workers · how to read it
| Pay level | Per year | Per month | Per hour* |
|---|---|---|---|
| Average | $118,850 | $9,904 | $57.14 |
| Median | $119,280 | $9,940 | $57.35 |
| Entry level (25th percentile) | $110,030 | $9,169 | $52.90 |
| Experienced (75th percentile) | $129,900 | $10,825 | $62.45 |
*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.
Nurse Practitioners pay in Greenville vs. South Carolina and the U.S.
Nurse practitioners in Greenville earn 4% less than the South Carolina average ($124,170) and 13% less than the U.S. average ($137,300). At the median the gap is -10% against the U.S. median of $132,300.
| Area | Average | Median | 10th pct. | 90th pct. | Jobs |
|---|---|---|---|---|---|
| Greenville | $118,850 | $119,280 | $81,910 | $145,570 | 1,120 |
| South Carolina | $124,170 | $123,290 | $97,080 | $160,170 | 5,670 |
| United States | $137,300 | $132,300 | $101,340 | $174,420 | 323,040 |
State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.
Nurse Practitioners salary after taxes in Greenville
On the average salary of $118,850, a single filer in Greenville takes home about $87,215 a year, or $7,268 a month and $3,354 every two weeks. Taxes take 27% of gross pay.
Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules).
Is Greenville a good place for nurse practitioners? Pay vs. cost of living
Prices in the Greenville area are 7% below the U.S. average (BEA price parity 93.3), so the average $118,850 buys what about $127,439 would buy in a typical U.S. metro. This job pays 2.6 times the median wage of all jobs in Greenville ($46,580). A typical home costs $315,285, or 2.7 years of this average salary before tax.
Nurse Practitioners salary in other South Carolina cities
Greenville ranks 6th of 8 South Carolina metro areas for this job; Spartanburg pays the most ($128,140).
- Spartanburg$128,140
- Florence$127,670
- Charleston$126,750
- Columbia$120,550
- Myrtle Beach$119,990
- Greenville$118,850
- Hilton Head Island$117,880
- Sumter$115,400
Highest-paying cities for nurse practitioners
San Jose, CA pays this job the most of the metro areas we cover ($225,610).
- San Jose, CA$225,610
- San Francisco, CA$215,430
- Vallejo, CA$196,780
- Napa, CA$188,720
- Modesto, CA$187,690
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Nurse Practitioners salary in Greenville: questions
How much do nurse practitioners make an hour in Greenville?
$57.14 an hour on average, and $57.35 at the median (BLS, May 2025).
What is the entry-level nurse practitioners salary in Greenville?
The lowest-paid 10% earn about $81,910 a year and the 25th percentile is $110,030, a fair guide to starting pay.
What is the nurse practitioners take-home pay in Greenville?
About $87,215 a year ($7,268 a month) for a single filer on the average salary of $118,850.
Do nurse practitioners earn more in Greenville than elsewhere?
The average here is 13% less than the U.S. average for this job ($137,300).
Sources and how to read this page
- Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1171; area Greenville-Anderson-Greer, SC (24860). Relative standard error of the mean wage: 2.3%.
- U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
- Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
- Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
- Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules).
- Job concentration: location quotient 1.24, this job is about as common as in the U.S. overall.
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