SOC 29-1171 · Winston-Salem, NC metro

Nurse Practitioners Salary in Winston-Salem, NC

The average salary for nurse practitioners in Winston-Salem, North Carolina is $133,740 a year ($64.30 an hour), according to BLS estimates for May 2025. The median is $130,840: half of the 750 people in this job in the Winston-Salem, NC metro area earn more than that, half earn less. That average is about the same as the U.S. average for this job ($137,300).

$133,740average per year

$64.30 / hourMedian $130,840Take-home ≈ $97,850

  • $105K10th
  • $117K25th
  • $131KMedian
  • $160K75th
  • $162K90th

median average · bar = middle 50% of workers · how to read it

750people in this job
-3%vs U.S. average
#4 of 15North Carolina metros
92cost of living (U.S. = 100)
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Nurse Practitioners pay range in Winston-Salem

New workers and the lowest-paid 10% earn about $105,120 a year or less, while the top 10% make $161,520 or more. The middle half of nurse practitioners in Winston-Salem earn between $117,010 and $160,200.

  • $105K10th
  • $117K25th
  • $131KMedian
  • $160K75th
  • $162K90th

median average · bar = middle 50% of workers · how to read it

Pay levelPer yearPer monthPer hour*
Average$133,740$11,145$64.30
Median$130,840$10,903$62.90
Entry level (25th percentile)$117,010$9,751$56.25
Experienced (75th percentile)$160,200$13,350$77.02

*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.

Nurse Practitioners pay in Winston-Salem vs. North Carolina and the U.S.

Nurse practitioners in Winston-Salem earn about the same as the North Carolina average ($130,870) and about the same as the U.S. average ($137,300). At the median the gap is -1% against the U.S. median of $132,300.

AreaAverageMedian10th pct.90th pct.Jobs
Winston-Salem$133,740$130,840$105,120$161,520750
North Carolina$130,870$128,990$103,530$164,3209,800
United States$137,300$132,300$101,340$174,420323,040

State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.

Nurse Practitioners salary after taxes in Winston-Salem

On the average salary of $133,740, a single filer in Winston-Salem takes home about $97,850 a year, or $8,154 a month and $3,763 every two weeks. Taxes take 27% of gross pay.

Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules).

North Carolina paycheck calculator: try your own salary

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Is Winston-Salem a good place for nurse practitioners? Pay vs. cost of living

Prices in the Winston-Salem area are 8% below the U.S. average (BEA price parity 92.0), so the average $133,740 buys what about $145,302 would buy in a typical U.S. metro. This job pays 2.8 times the median wage of all jobs in Winston-Salem ($46,380). A typical home costs $283,871, or 2.1 years of this average salary before tax.

See what $133,740 is worth in another city

Nurse Practitioners salary in other North Carolina cities

Winston-Salem ranks 4th of 15 North Carolina metro areas for this job; Burlington pays the most ($137,850).

All Nurse Practitioners salaries in North Carolina

Highest-paying cities for nurse practitioners

San Jose, CA pays this job the most of the metro areas we cover ($225,610).

Nurse Practitioners salary by city

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Reviewed before it counts. Nurse Practitioners in Winston-Salem, NC.

Nurse Practitioners salary in Winston-Salem: questions

How much do nurse practitioners make an hour in Winston-Salem?

$64.30 an hour on average, and $62.90 at the median (BLS, May 2025).

What is the entry-level nurse practitioners salary in Winston-Salem?

The lowest-paid 10% earn about $105,120 a year and the 25th percentile is $117,010, a fair guide to starting pay.

What is the nurse practitioners take-home pay in Winston-Salem?

About $97,850 a year ($8,154 a month) for a single filer on the average salary of $133,740.

Do nurse practitioners earn more in Winston-Salem than elsewhere?

The average here is about the same as the U.S. average for this job ($137,300).

Sources and how to read this page

  • Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1171; area Winston-Salem, NC (49180). Relative standard error of the mean wage: 0.8%.
  • U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
  • Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
  • Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
  • Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules).
  • Job concentration: location quotient 1.32, this job is 1.3 times as concentrated as in the U.S. overall.

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