SOC 29-1171 · Sioux City, IA-NE-SD metro

Nurse Practitioners Salary in Sioux City, IA

The average salary for nurse practitioners in Sioux City, Iowa is $135,460 a year ($65.13 an hour), according to BLS estimates for May 2025. The median is $129,060: half of the 150 people in this job in the Sioux City, IA-NE-SD metro area earn more than that, half earn less. That average is about the same as the U.S. metro average for this job ($138,268).

$135,460average per year

$65.13 / hourMedian $129,060Take-home ≈ $99,317

  • $107K10th
  • $120K25th
  • $129KMedian
  • $143K75th
  • $163K90th

median average · bar = middle 50% of workers

150people in this job
-2%vs U.S. metro average
#3 of 8Iowa metros
86cost of living (U.S. = 100)
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Nurse Practitioners pay range in Sioux City

New workers and the lowest-paid 10% earn about $106,750 a year or less, while the top 10% make $162,540 or more. The middle half of nurse practitioners in Sioux City earn between $119,950 and $142,830.

  • $107K10th
  • $120K25th
  • $129KMedian
  • $143K75th
  • $163K90th

median average · bar = middle 50% of workers

Pay levelPer yearPer monthPer hour*
Average$135,460$11,288$65.12
Median$129,060$10,755$62.05
Entry level (25th percentile)$119,950$9,996$57.67
Experienced (75th percentile)$142,830$11,902$68.67

*Hourly figures assume 2,080 paid hours a year.

Nurse Practitioners salary after taxes in Sioux City

On the average salary of $135,460, a single filer in Sioux City takes home about $99,317 a year, or $8,276 a month and $3,820 every two weeks. Taxes take 27% of gross pay.

The Sioux City, IA-NE-SD metro area crosses state lines, so take-home pay depends on the state where you work:

StatePer yearPer month
Working in SD$103,853$8,654
Working in IA$99,317$8,276
Working in NE$98,569$8,214

Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules). Iowa school district surtaxes (a percentage of state tax in some districts) are not included.

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Is Sioux City a good place for nurse practitioners? Pay vs. cost of living

Prices in the Sioux City area are 14% below the U.S. average (BEA price parity 86.5), so the average $135,460 buys what about $156,684 would buy in a typical U.S. metro. This job pays 2.7 times the median wage of all jobs in Sioux City ($47,030). A typical home costs $225,213, or 1.7 years of this average salary before tax.

See what $135,460 is worth in another city

Nurse Practitioners salary in other Iowa cities

Sioux City ranks 3rd of 8 Iowa metro areas for this job; Des Moines pays the most ($138,820).

All Nurse Practitioners salaries in Iowa

Highest-paying cities for nurse practitioners

San Jose, CA pays this job the most of the metro areas we cover ($225,610).

Nurse Practitioners salary by city

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Reviewed before it counts. Nurse Practitioners in Sioux City, IA.

Nurse Practitioners salary in Sioux City: questions

How much do nurse practitioners make an hour in Sioux City?

$65.13 an hour on average, and $62.05 at the median (BLS, May 2025).

What is the entry-level nurse practitioners salary in Sioux City?

The lowest-paid 10% earn about $106,750 a year and the 25th percentile is $119,950, a fair guide to starting pay.

What is the nurse practitioners take-home pay in Sioux City?

About $99,317 a year ($8,276 a month) for a single filer on the average salary of $135,460. Iowa school district surtaxes (a percentage of state tax in some districts) are not included.

Do nurse practitioners earn more in Sioux City than elsewhere?

The average here is about the same as the U.S. metro average for this job ($138,268).

Sources and how to read this page

  • Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1171; area Sioux City, IA-NE-SD (43580). Relative standard error of the mean wage: 2.3%.
  • Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
  • Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
  • Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules). Iowa school district surtaxes (a percentage of state tax in some districts) are not included.
  • Job concentration: location quotient 0.94, this job is about as common as in the U.S. overall.

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