SOC 29-1216 · Charleston-North Charleston, SC metro

General Internal Medicine Physicians Salary in Charleston, SC

The average salary for general internal medicine physicians in Charleston, South Carolina is $340,400 a year ($163.65 an hour), according to BLS estimates for May 2025. The median is $303,680: half of the 80 people in this job in the Charleston-North Charleston, SC metro area earn more than that, half earn less. That average is 27% more than the U.S. average for this job ($267,200).

$340,400average per year

$163.65 / hourMedian $303,680Take-home ≈ $223,719

  • $201K10th
  • $240K25th
  • $304KMedian
  • $496K75th
  • $521K90th

median average · bar = middle 50% of workers · how to read it

80people in this job
+27%vs U.S. average
#1 of 4South Carolina metros
101cost of living (U.S. = 100)
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General Internal Medicine Physicians pay range in Charleston

New workers and the lowest-paid 10% earn about $200,960 a year or less, while the top 10% make $520,790 or more. The middle half of general internal medicine physicians in Charleston earn between $239,600 and $496,240.

  • $201K10th
  • $240K25th
  • $304KMedian
  • $496K75th
  • $521K90th

median average · bar = middle 50% of workers · how to read it

Pay levelPer yearPer monthPer hour*
Average$340,400$28,367$163.65
Median$303,680$25,307$146.00
Entry level (25th percentile)$239,600$19,967$115.19
Experienced (75th percentile)$496,240$41,353$238.58

*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.

General Internal Medicine Physicians pay in Charleston vs. South Carolina and the U.S.

General internal medicine physicians in Charleston earn 8% more than the South Carolina average ($315,380) and 27% more than the U.S. average ($267,200). At the median the gap is +18% against the U.S. median of $256,560.

AreaAverageMedian10th pct.90th pct.Jobs
Charleston$340,400$303,680$200,960$520,79080
South Carolina$315,380$359,500$102,500$441,0101,260
United States$267,200$256,560$73,570$475,43067,150

State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.

General Internal Medicine Physicians salary after taxes in Charleston

On the average salary of $340,400, a single filer in Charleston takes home about $223,719 a year, or $18,643 a month and $8,605 every two weeks. Taxes take 34% of gross pay.

Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules).

South Carolina paycheck calculator: try your own salary

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Is Charleston a good place for general internal medicine physicians? Pay vs. cost of living

Prices in the Charleston area are in line with the U.S. average (BEA price parity 101.0), so the average $340,400 buys what about $337,157 would buy in a typical U.S. metro. This job pays 6.2 times the median wage of all jobs in Charleston ($49,150). A typical home costs $435,877, or 1.3 years of this average salary before tax.

See what $340,400 is worth in another city

General Internal Medicine Physicians salary in other South Carolina cities

Charleston ranks 1st of 4 South Carolina metro areas for this job, the best-paid in the state.

All General Internal Medicine Physicians salaries in South Carolina

Highest-paying cities for general internal medicine physicians

South Bend, IN pays this job the most of the metro areas we cover ($424,610).

General Internal Medicine Physicians salary by city

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Reviewed before it counts. General Internal Medicine Physicians in Charleston, SC.

General Internal Medicine Physicians salary in Charleston: questions

How much do general internal medicine physicians make an hour in Charleston?

$163.65 an hour on average, and $146.00 at the median (BLS, May 2025).

What is the entry-level general internal medicine physicians salary in Charleston?

The lowest-paid 10% earn about $200,960 a year and the 25th percentile is $239,600, a fair guide to starting pay.

What is the general internal medicine physicians take-home pay in Charleston?

About $223,719 a year ($18,643 a month) for a single filer on the average salary of $340,400.

Do general internal medicine physicians earn more in Charleston than elsewhere?

The average here is 27% more than the U.S. average for this job ($267,200).

Sources and how to read this page

  • Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 29-1216; area Charleston-North Charleston, SC (16700). Relative standard error of the mean wage: 17.7%.
  • U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
  • Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
  • Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
  • Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2026 rules).
  • Job concentration: location quotient 0.49, this job is less common than in the U.S. overall (location quotient 0.49).

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