SOC 19-1021 · Buffalo-Cheektowaga, NY metro

Biochemists and Biophysicists Salary in Buffalo, NY

The average salary for biochemists and biophysicists in Buffalo, New York is $102,490 a year ($49.27 an hour), according to BLS estimates for May 2025. The median is $81,480: half of the 80 people in this job in the Buffalo-Cheektowaga, NY metro area earn more than that, half earn less. That average is 21% less than the U.S. average for this job ($129,840).

$102,490average per year

$49.27 / hourMedian $81,480Take-home ≈ $75,831

  • $59K10th
  • $67K25th
  • $81KMedian
  • $104K75th
  • $211K90th

median average · bar = middle 50% of workers · how to read it

80people in this job
-21%vs U.S. average
#3 of 3New York metros
96cost of living (U.S. = 100)
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Biochemists and Biophysicists pay range in Buffalo

New workers and the lowest-paid 10% earn about $58,880 a year or less, while the top 10% make $210,520 or more. The middle half of biochemists and biophysicists in Buffalo earn between $66,620 and $103,530.

  • $59K10th
  • $67K25th
  • $81KMedian
  • $104K75th
  • $211K90th

median average · bar = middle 50% of workers · how to read it

Pay levelPer yearPer monthPer hour*
Average$102,490$8,541$49.27
Median$81,480$6,790$39.17
Entry level (25th percentile)$66,620$5,552$32.03
Experienced (75th percentile)$103,530$8,628$49.77

*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.

Biochemists and Biophysicists pay in Buffalo vs. New York and the U.S.

Biochemists and biophysicists in Buffalo earn 5% less than the New York average ($108,140) and 21% less than the U.S. average ($129,840). At the median the gap is -36% against the U.S. median of $127,410.

AreaAverageMedian10th pct.90th pct.Jobs
Buffalo$102,490$81,480$58,880$210,52080
New York$108,140$101,080$66,140$165,710980
United States$129,840$127,410$74,290$201,11033,830

State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.

Biochemists and Biophysicists salary after taxes in Buffalo

On the average salary of $102,490, a single filer in Buffalo takes home about $75,831 a year, or $6,319 a month and $2,917 every two weeks. Taxes take 26% of gross pay.

Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2025 rules). New York City (up to 3.876%) and Yonkers income taxes are not included.

New York paycheck calculator: try your own salary

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Is Buffalo a good place for biochemists and biophysicists? Pay vs. cost of living

Prices in the Buffalo area are 4% below the U.S. average (BEA price parity 95.8), so the average $102,490 buys what about $106,934 would buy in a typical U.S. metro. This job pays 1.6 times the median wage of all jobs in Buffalo ($50,790). A typical home costs $288,316, or 2.8 years of this average salary before tax.

See what $102,490 is worth in another city

Biochemists and Biophysicists salary in other New York cities

Buffalo ranks 3rd of 3 New York metro areas for this job; New York pays the most ($119,540).

All Biochemists and Biophysicists salaries in New York

Highest-paying cities for biochemists and biophysicists

Jacksonville, FL pays this job the most of the metro areas we cover ($170,200).

Biochemists and Biophysicists salary by city

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Biochemists and Biophysicists salary in Buffalo: questions

How much do biochemists and biophysicists make an hour in Buffalo?

$49.27 an hour on average, and $39.17 at the median (BLS, May 2025).

What is the entry-level biochemists and biophysicists salary in Buffalo?

The lowest-paid 10% earn about $58,880 a year and the 25th percentile is $66,620, a fair guide to starting pay.

What is the biochemists and biophysicists take-home pay in Buffalo?

About $75,831 a year ($6,319 a month) for a single filer on the average salary of $102,490. New York City (up to 3.876%) and Yonkers income taxes are not included.

Do biochemists and biophysicists earn more in Buffalo than elsewhere?

The average here is 21% less than the U.S. average for this job ($129,840).

Sources and how to read this page

  • Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 19-1021; area Buffalo-Cheektowaga, NY (15380). Relative standard error of the mean wage: 6.8%.
  • U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
  • Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
  • Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
  • Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2025 rules). New York City (up to 3.876%) and Yonkers income taxes are not included.
  • Job concentration: location quotient 0.66, this job is less common than in the U.S. overall (location quotient 0.66).

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