SOC 19-1021 · San Diego-Chula Vista-Carlsbad, CA metro

Biochemists and Biophysicists Salary in San Diego, CA

The average salary for biochemists and biophysicists in San Diego, California is $126,920 a year ($61.02 an hour), according to BLS estimates for May 2025. The median is $121,740: half of the 710 people in this job in the San Diego-Chula Vista-Carlsbad, CA metro area earn more than that, half earn less. That average is about the same as the U.S. average for this job ($129,840).

$126,920average per year

$61.02 / hourMedian $121,740Take-home ≈ $90,304

  • $74K10th
  • $90K25th
  • $122KMedian
  • $154K75th
  • $199K90th

median average · bar = middle 50% of workers · how to read it

710people in this job
-2%vs U.S. average
#5 of 5California metros
112cost of living (U.S. = 100)
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Biochemists and Biophysicists pay range in San Diego

New workers and the lowest-paid 10% earn about $73,590 a year or less, while the top 10% make $199,060 or more. The middle half of biochemists and biophysicists in San Diego earn between $89,980 and $154,200.

  • $74K10th
  • $90K25th
  • $122KMedian
  • $154K75th
  • $199K90th

median average · bar = middle 50% of workers · how to read it

Pay levelPer yearPer monthPer hour*
Average$126,920$10,577$61.02
Median$121,740$10,145$58.53
Entry level (25th percentile)$89,980$7,498$43.26
Experienced (75th percentile)$154,200$12,850$74.13

*Hourly figures assume 2,080 paid hours a year. Hourly to annual salary.

Biochemists and Biophysicists pay in San Diego vs. California and the U.S.

Biochemists and biophysicists in San Diego earn 15% less than the California average ($148,550) and about the same as the U.S. average ($129,840). At the median the gap is -4% against the U.S. median of $127,410.

AreaAverageMedian10th pct.90th pct.Jobs
San Diego$126,920$121,740$73,590$199,060710
California$148,550$139,580$83,580$208,2103,240
United States$129,840$127,410$74,290$201,11033,830

State and U.S. rows: BLS statewide and national estimates, May 2025, which include rural areas.

Biochemists and Biophysicists salary after taxes in San Diego

On the average salary of $126,920, a single filer in San Diego takes home about $90,304 a year, or $7,525 a month and $3,473 every two weeks. Taxes take 29% of gross pay.

Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2025 rules). California State Disability Insurance (1.3% of wages, paid by employees) is not included.

California paycheck calculator: try your own salary

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Is San Diego a good place for biochemists and biophysicists? Pay vs. cost of living

Prices in the San Diego area are 12% above the U.S. average (BEA price parity 111.9), so the average $126,920 buys what about $113,436 would buy in a typical U.S. metro. This job pays 2.1 times the median wage of all jobs in San Diego ($58,690). A typical home costs $946,365, or 7.5 years of this average salary before tax.

See what $126,920 is worth in another city

Biochemists and Biophysicists salary in other California cities

San Diego ranks 5th of 5 California metro areas for this job; San Francisco pays the most ($168,650).

All Biochemists and Biophysicists salaries in California

Highest-paying cities for biochemists and biophysicists

Jacksonville, FL pays this job the most of the metro areas we cover ($170,200).

Biochemists and Biophysicists salary by city

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Biochemists and Biophysicists salary in San Diego: questions

How much do biochemists and biophysicists make an hour in San Diego?

$61.02 an hour on average, and $58.53 at the median (BLS, May 2025).

What is the entry-level biochemists and biophysicists salary in San Diego?

The lowest-paid 10% earn about $73,590 a year and the 25th percentile is $89,980, a fair guide to starting pay.

What is the biochemists and biophysicists take-home pay in San Diego?

About $90,304 a year ($7,525 a month) for a single filer on the average salary of $126,920. California State Disability Insurance (1.3% of wages, paid by employees) is not included.

Do biochemists and biophysicists earn more in San Diego than elsewhere?

The average here is about the same as the U.S. average for this job ($129,840).

Sources and how to read this page

  • Wages: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 estimates for metropolitan areas. SOC code 19-1021; area San Diego-Chula Vista-Carlsbad, CA (41740). Relative standard error of the mean wage: 3.1%.
  • U.S. and statewide figures: BLS OEWS national and state estimates, May 2025, every employer including rural areas.
  • Cost of living: Bureau of Economic Analysis regional price parities (RPP), 2024; 100 = U.S. average.
  • Home value: Zillow Home Value Index. Typical-wage figure: OEWS all occupations, same metro.
  • Take-home pay: Single filer, standard deduction: federal income tax (2026 brackets), Social Security, Medicare and state income tax (2025 rules). California State Disability Insurance (1.3% of wages, paid by employees) is not included.
  • Job concentration: location quotient 2.13, this job is 2.1 times as concentrated as in the U.S. overall.

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